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Reversal of intrinsic multidrug resistance in Chinese hamster ovary cells by amiloride analogs.

A number of amiloride analogs can sensitise wild type Chinese Hamster ovary (CHO) cells to the cytotoxic action of vinblastine, daunomycin, puromycin or colchicine. Some of these analogs also have weak sensitising effects on the multidrug resistant CHO cell line, CHRC5. The unusual feature of most o...

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Détails bibliographiques
Auteurs principaux: Epand, R. F., Epand, R. M., Gupta, R. S., Cragoe, E. J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1971774/
https://ncbi.nlm.nih.gov/pubmed/1671752
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