Bitter and sweet taste receptors regulate human upper respiratory innate immunity

Bitter taste receptors (T2Rs) in the human airway detect harmful compounds, including secreted bacterial products. Here, using human primary sinonasal air-liquid interface cultures and tissue explants, we determined that activation of a subset of airway T2Rs expressed in nasal solitary chemosensory...

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Detalles Bibliográficos
Main Authors: Lee, Robert J., Kofonow, Jennifer M., Rosen, Philip L., Siebert, Adam P., Chen, Bei, Doghramji, Laurel, Xiong, Guoxiang, Adappa, Nithin D., Palmer, James N., Kennedy, David W., Kreindler, James L., Margolskee, Robert F., Cohen, Noam A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934184/
https://ncbi.nlm.nih.gov/pubmed/24531552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72094
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