Infidelity of DNA synthesis associated with bypass of apurinic sites.

The mutagenic potential of apurinic sites in vivo has been studied by transfection of depurinated phi X174 DNA containing amber mutations into SOS-induced Escherichia coli spheroplasts. Mutagenicity is abolished by treatment of the depurinated DNA with an apurinic endonuclease from Hela cells, estab...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Schaaper, R M, Kunkel, T A, Loeb, L A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1983
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393403/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300848/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.2.487
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