Mutagenesis during in vitro DNA synthesis.

The error frequency of in vitro DNA synthesis using a natural DNA template has been measured with a biological assay for nucleotide substitutions. phiX174 DNA containing an amber mutation was copied in vitro by Escherichia coli DNA polymerase I, and the reversion frequency of the progeny DNA was det...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Weymouth, L A, Loeb, L A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1978
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392454/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/347450/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.4.1924
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