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Infidelity of DNA synthesis associated with bypass of apurinic sites.

The mutagenic potential of apurinic sites in vivo has been studied by transfection of depurinated phi X174 DNA containing amber mutations into SOS-induced Escherichia coli spheroplasts. Mutagenicity is abolished by treatment of the depurinated DNA with an apurinic endonuclease from Hela cells, estab...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Schaaper, R M, Kunkel, T A, Loeb, L A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393403/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300848/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.2.487
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