Restoring visual function to blind mice with a photoswitch that exploits electrophysiological remodeling of retinal ganglion cells

Retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are blinding diseases caused by the degeneration of rods and cones, leaving the remainder of the visual system unable to respond to light. Here we report a chemical photoswitch named DENAQ that restores retinal responses to white l...

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Bibliografische gegevens
Hoofdauteurs: Tochitsky, Ivan, Polosukhina, Aleksandra, Degtyar, Vadim E., Gallerani, Nicholas, Smith, Caleb M., Friedman, Aaron, Van Gelder, Russell N., Trauner, Dirk, Kaufer, Daniela, Kramer, Richard H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933823/
https://ncbi.nlm.nih.gov/pubmed/24559673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.01.003
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