Photochemical restoration of visual responses in blind mice

Retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are degenerative blinding diseases caused by the death of rods and cones, leaving the remainder of the visual system intact but largely unable to respond to light. Here we show that, AAQ, a synthetic small molecule photoswitch, can...

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Bibliografiske detaljer
Main Authors: Polosukhina, Aleksandra, Litt, Jeffrey, Tochitsky, Ivan, Nemargut, Joseph, Sychev, Yivgeny, De Kouchkovsky, Ivan, Huang, Tracy, Borges, Katharine, Trauner, Dirk, Van Gelder, Russell N., Kramer, Richard H.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408583/
https://ncbi.nlm.nih.gov/pubmed/22841312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.05.022
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