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LiGluR Restores Visual Responses in Rodent Models of Inherited Blindness

Inherited retinal degeneration results from many different mutations in either photoreceptor-specific or nonphotoreceptor-specific genes. However, nearly all mutations lead to a common blinding phenotype that initiates with rod cell death, followed by loss of cones. In most retinal degenerations, ot...

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Detalhes bibliográficos
Main Authors: Caporale, Natalia, Kolstad, Kathleen D, Lee, Trevor, Tochitsky, Ivan, Dalkara, Deniz, Trauner, Dirk, Kramer, Richard, Dan, Yang, Isacoff, Ehud Y, Flannery, John G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129552/
https://ncbi.nlm.nih.gov/pubmed/21610698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.103
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