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Rapid optical control of nociception with an ion channel photoswitch
Local anesthetics are effective in suppressing pain sensation, but most of these compounds act non-selectively, inhibiting the activity of all neurons. Moreover, their actions abate slowly, preventing precise spatial and temporal control of nociception. We have developed a photoisomerizable molecule...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906498/ https://ncbi.nlm.nih.gov/pubmed/22343342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1897 |
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