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Tropheryma whipplei, the Agent of Whipple's Disease, Affects the Early to Late Phagosome Transition and Survives in a Rab5- and Rab7-Positive Compartment

Tropheryma whipplei, the agent of Whipple's disease, inhibits phago-lysosome biogenesis to create a suitable niche for its survival and replication in macrophages. To understand the mechanism by which it subverts phagosome maturation, we used biochemical and cell biological approaches to purify...

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Autors principals: Mottola, Giovanna, Boucherit, Nicolas, Trouplin, Virginie, Oury Barry, Abdoulaye, Soubeyran, Philippe, Mege, Jean-Louis, Ghigo, Eric
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933534/
https://ncbi.nlm.nih.gov/pubmed/24586722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089367
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