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Tropheryma whipplei, the Whipple's disease bacillus, induces macrophage apoptosis through the extrinsic pathway

Tropheryma whipplei, the etiological agent of Whipple's disease, is an intracellular bacterium that infects macrophages. We previously showed that infection of macrophages results in M2 polarization associated with induction of apoptosis and interleukin (IL)-16 secretion. In patients with Whipp...

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Detalhes bibliográficos
Main Authors: Gorvel, L, Al Moussawi, K, Ghigo, E, Capo, C, Mege, J-L, Desnues, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032299/
https://ncbi.nlm.nih.gov/pubmed/21364641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.11
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