Tropheryma whipplei, the Whipple's disease bacillus, induces macrophage apoptosis through the extrinsic pathway

Tropheryma whipplei, the etiological agent of Whipple's disease, is an intracellular bacterium that infects macrophages. We previously showed that infection of macrophages results in M2 polarization associated with induction of apoptosis and interleukin (IL)-16 secretion. In patients with Whipp...

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Main Authors: Gorvel, L, Al Moussawi, K, Ghigo, E, Capo, C, Mege, J-L, Desnues, B
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032299/
https://ncbi.nlm.nih.gov/pubmed/21364641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2010.11
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