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IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation.

The replication of Tropheryma whipplei (the agent of Whipple's disease) within human macrophages is associated with the expression of IL-16, a cytokine known for its chemotactic and inflammatory properties. In this study, we asked whether IL-16 acts on T. whipplei replication by interfering wit...

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Detalhes bibliográficos
Main Authors: Eric Ghigo, Abdoulaye Oury Barry, Lionel Pretat, Khatoun Al Moussawi, Benoît Desnues, Christian Capo, Hardy Kornfeld, Jean-Louis Mege
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2958842?pdf=render
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