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Synthesis and Properties of a Selective Inhibitor of Homeodomain–Interacting Protein Kinase 2 (HIPK2)

Homeodomain-interacting protein kinase 2 (HIPK2) is a Ser/Thr kinase controlling cell proliferation and survival, whose investigation has been hampered by the lack of specific inhibitors able to dissect its cellular functions. SB203580, a p38 MAP kinase inhibitor, has been used as a tool to inhibit...

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Библиографические подробности
Главные авторы: Cozza, Giorgio, Zanin, Sofia, Determann, Renate, Ruzzene, Maria, Kunick, Conrad, Pinna, Lorenzo A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933419/
https://ncbi.nlm.nih.gov/pubmed/24586573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089176
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