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Homeodomain-interacting protein kinase 2 (HIPK2): a promising target for anti-cancer therapies

The HIPK2 (serine/threonine homeodomain-interacting protein kinase 2) is a “caretaker” gene, its inactivation increases tumorigenicity while its activation inhibits tumor growth. This report reviews the anti-tumorigenic mechanisms of HIPK2, which include promotion of apoptosis, inhibition of angioge...

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Publicat a:Oncotarget
Autors principals: Feng, Yuanyuan, Zhou, Lihong, Sun, Xiaoting, Li, Qi
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386776/
https://ncbi.nlm.nih.gov/pubmed/28107201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14723
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