Abnormal Expression Pattern of the IL-2 Receptor β-Chain on CD4(+) T Cells in ANCA-Associated Vasculitis

Background/Aim. ANCA-associated vasculitis (AAV) is a small-vessel vasculitis of autoimmune origin. In addition to autoantibodies, T cells have a pivotal pathophysiological role in this disease. T-cell homeostasis and immune tolerance critically depend on IL-2 and its receptor expressed by T cells....

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Main Authors: Wilde, Benjamin, Hoerning, André, Kribben, Andreas, Witzke, Oliver, Dolff, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933302/
https://ncbi.nlm.nih.gov/pubmed/24648606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/249846
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