The Co-inhibitor BTLA Is Functional in ANCA-Associated Vasculitis and Suppresses Th17 Cells

Objectives: The activation and inhibition of T-cells has been well-studied under physiological conditions. Co-inhibition is an important mechanism to keep effector T-cells in check. Co-inhibitors mediate peripheral self-tolerance and limit the immune response. Dysfunctional co-inhibition is associat...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Werner, Kai, Dolff, Sebastian, Dai, Yang, Ma, Xin, Brinkhoff, Alexandra, Korth, Johannes, Gäckler, Anja, Rohn, Hana, Sun, Ming, Cohen Tervaert, Jan Willem, van Paassen, Pieter, Kribben, Andreas, Witzke, Oliver, Wilde, Benjamin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914808/
https://ncbi.nlm.nih.gov/pubmed/31921121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02843
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