Renal Transplant Recipients Treated with Calcineurin-Inhibitors Lack Circulating Immature Transitional CD19(+)CD24(hi)CD38(hi) Regulatory B-Lymphocytes

BACKGROUND: CD19(+)CD24(hi)CD38(hi) transitional immature B-lymphocytes have been demonstrated to play an important role in regulating the alloimmune response in transplant recipients. Here, we analyzed the effect of calcineurin inhibition on these peripherally circulating regulatory B-cells (Breg)...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Tebbe, Bastian, Wilde, Benjamin, Ye, Zeng, Wang, Junyu, Wang, Xinning, Jian, Fu, Dolff, Sebastian, Schedlowski, Manfred, Hoyer, Peter F., Kribben, Andreas, Witzke, Oliver, Hoerning, André
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4821620/
https://ncbi.nlm.nih.gov/pubmed/27045291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153170
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