Human Lung Mast Cell Products Regulate Airway Smooth Muscle CXCL10 Levels

In asthma, the airway smooth muscle (ASM) produces CXCL10 which may attract CXCR3(+) mast/T cells to it. Our aim was to investigate the effects of mast cell products on ASM cell CXCL10 production. ASM cells from people with and without asthma were stimulated with IL-1β, TNF-α, and/or IFNγ and treate...

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Главные авторы: Alkhouri, H., Cha, V., Tong, K., Moir, L. M., Armour, C. L., Hughes, J. M.
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933026/
https://ncbi.nlm.nih.gov/pubmed/24648846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/875105
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