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Asthmatic airway smooth muscle CXCL10 production: mitogen-activated protein kinase JNK involvement

CXCL10 (IP10) is involved in mast cell migration to airway smooth muscle (ASM) bundles in asthma. We aimed to investigate the role of cytokine-induced MAPK activation in CXCL10 production by ASM cells from people with and without asthma. Confluent growth-arrested ASM cells were treated with inhibito...

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Autors principals: Alrashdan, Yazan A., Alkhouri, Hatem, Chen, Emily, Lalor, Daniel J., Poniris, Maree, Henness, Sheridan, Brightling, Christopher E., Burgess, Janette K., Armour, Carol L., Ammit, Alaina J., Margaret Hughes, J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362261/
https://ncbi.nlm.nih.gov/pubmed/22387292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00232.2011
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