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Induction of an antiviral response by interferon requires thymidine kinase.

Mouse fibroblastoid cells (Ltk-) that lack thymidine kinase (tk) activity are unable to respond to murine beta-interferon by establishing antiviral activity or inducing the double-stranded RNA-dependent enzymes, oligo[(2'-5')A] polymerase and Mr 68,000 protein kinase. In contrast, the pare...

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Detalles Bibliográficos
Main Authors: Lewis, J A, Mengheri, E, Esteban, M
Formato: Artigo
Idioma:Inglês
Publicado: 1983
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC393302/
https://ncbi.nlm.nih.gov/pubmed/6185957
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