Structural basis for nuclear import of splicing factors by human Transportin 3

Transportin 3 (Tnpo3, Transportin-SR2) is implicated in nuclear import of splicing factors and HIV-1 replication. Herein, we show that the majority of cellular Tnpo3 binding partners contain arginine-serine (RS) repeat domains and present crystal structures of human Tnpo3 in its free as well as GTPa...

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Xehetasun bibliografikoak
Egile Nagusiak: Maertens, Goedele N., Cook, Nicola J., Wang, Weifeng, Hare, Stephen, Gupta, Saumya Shree, Öztop, Ilker, Lee, KyeongEun, Pye, Valerie E., Cosnefroy, Ophélie, Snijders, Ambrosius P., KewalRamani, Vineet N., Fassati, Ariberto, Engelman, Alan, Cherepanov, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932936/
https://ncbi.nlm.nih.gov/pubmed/24449914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320755111
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