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Differential response of regulatory and conventional CD4(+) lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action?
Several clinical trials have shown anti-CD3 treatment to be a promising therapy for autoimmune diabetes, but its mechanism of action remains unclear. Foxp3(+) regulatory T (Treg) cells are likely to be involved, but through unknown mechanistic pathways. We profiled the transcriptional consequences i...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932531/ https://ncbi.nlm.nih.gov/pubmed/23986534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300408 |
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