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An essential relationship between ATP depletion and chemosensitizing activity of Pluronic® block copolymers

Pluronic® block copolymers are known to sensitize multidrug resistant (MDR) tumors with respect to various anticancer agents, particularly, anthracycline antibiotics. After completion of the Phase I clinical trial, the formulation containing doxorubicin and Pluronic®, SP1049C, is undergoing Phase II...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kabanov, Alexander V., Batrakova, Elena V., Alakhov, Valery Yu.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932490/
https://ncbi.nlm.nih.gov/pubmed/12932639
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