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Heme oxygenase-1 protects regulatory T cells from hypoxia-induced cellular stress in an experimental mouse brain tumor model
Two characteristic features of malignant gliomas (MG) are the presence of hypoxia and accumulation of regulatory T cells (Treg). Heme-oxygenase-1 (HO1) is a cytoprotective enzyme expressed in high level by Tregs in glioma. In this study, we show that higher HO1 expression in Treg is associated with...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3932190/ https://ncbi.nlm.nih.gov/pubmed/24268287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2013.10.012 |
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