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Targeting Tregs in Malignant Brain Cancer: Overcoming IDO
One of the hallmark features of glioblastoma multiforme (GBM), the most common adult primary brain tumor with a very dismal prognosis, is the accumulation of CD4(+)CD25(+)Foxp3(+) regulatory T cells (Tregs). Regulatory T cells (Tregs) segregate into two primary categories: thymus-derived natural Tre...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654236/ https://ncbi.nlm.nih.gov/pubmed/23720663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00116 |
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