Unique features of the transcriptional response to model aneuploidy in human cells

BACKGROUND: Aneuploidy, a karyotype deviating from multiples of a haploid chromosome set, affects the physiology of eukaryotes. In humans, aneuploidy is linked to pathological defects such as developmental abnormalities, mental retardation or cancer, but the underlying mechanisms remain elusive. The...

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Main Authors: Dürrbaum, Milena, Kuznetsova, Anastasia Yurievna, Passerini, Verena, Stingele, Silvia, Stoehr, Gabriele, Storchová, Zuzana
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932016/
https://ncbi.nlm.nih.gov/pubmed/24548329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-139
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