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Unique features of the transcriptional response to model aneuploidy in human cells

BACKGROUND: Aneuploidy, a karyotype deviating from multiples of a haploid chromosome set, affects the physiology of eukaryotes. In humans, aneuploidy is linked to pathological defects such as developmental abnormalities, mental retardation or cancer, but the underlying mechanisms remain elusive. The...

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Detalhes bibliográficos
Main Authors: Dürrbaum, Milena, Kuznetsova, Anastasia Yurievna, Passerini, Verena, Stingele, Silvia, Stoehr, Gabriele, Storchová, Zuzana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932016/
https://ncbi.nlm.nih.gov/pubmed/24548329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-139
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