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Unique features of the transcriptional response to model aneuploidy in human cells

BACKGROUND: Aneuploidy, a karyotype deviating from multiples of a haploid chromosome set, affects the physiology of eukaryotes. In humans, aneuploidy is linked to pathological defects such as developmental abnormalities, mental retardation or cancer, but the underlying mechanisms remain elusive. The...

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Bibliographische Detailangaben
Hauptverfasser: Dürrbaum, Milena, Kuznetsova, Anastasia Yurievna, Passerini, Verena, Stingele, Silvia, Stoehr, Gabriele, Storchová, Zuzana
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932016/
https://ncbi.nlm.nih.gov/pubmed/24548329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-139
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