Role of the ERK Pathway for Oxidant-Induced Parthanatos in Human Lymphocytes

Reactive oxygen species (ROS) are formed by myeloid cells as a defense strategy against microorganisms. ROS however also trigger poly(ADP-ribose) polymerase 1- (PARP-1) dependent cell death (parthanatos) in adjacent lymphocytes, which has been forwarded as a mechanism of immune escape in several for...

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Detalhes bibliográficos
Main Authors: Akhiani, Ali A., Werlenius, Olle, Aurelius, Johan, Movitz, Charlotta, Martner, Anna, Hellstrand, Kristoffer, Thorén, Fredrik B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931820/
https://ncbi.nlm.nih.gov/pubmed/24586933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089646
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