Tsc1-Tp53 loss induces mesothelioma in mice, and evidence for this mechanism in human mesothelioma

Mesothelioma is diagnosed in approximately 2,500 patients in the United States every year, most often arising in the pleural space, but also occurring as primary peritoneal mesothelioma. The vast majority of patients with mesothelioma die from their disease within 3 years. We developed a new mouse m...

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Bibliographic Details
Main Authors: Guo, Yanan, Chirieac, Lucian R., Bueno, Raphael, Pass, Harvey, Wu, Wenhao, Malinowska, Izabela A., Kwiatkowski, David J.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931745/
https://ncbi.nlm.nih.gov/pubmed/23851502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.280
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