Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine.
The antihistamine [3H]mepyramine binds to H1 histamine receptors in mammalian brain membranes. Potencies of H1 antihistamines at the binding sites correlate with their pharmacological antihistamine effects in the guinea pig ileum. Specific [3H]mepyramine binding is saturable with a dissociation cons...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1978
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/282646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.6290 |
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