Autoregulation of bradykinin receptors and bradykinin-induced prostacyclin formation in human fibroblasts.

The interaction of bradykinin (BK) with its specific receptors on intact cultured human fibroblasts results in production of prostaglandins, including prostacyclin (PGI2), and accumulation of cyclic AMP. Incubation of cells with 1 microM BK for 5 min at 37 degrees C led to a marked reduction (75-90%...

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Main Authors: Roscher, A A, Manganiello, V C, Jelsema, C L, Moss, J
格式: Artigo
語言:Inglês
出版: 1984
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC370507/
https://ncbi.nlm.nih.gov/pubmed/6146639
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