Autoregulation of bradykinin receptors and bradykinin-induced prostacyclin formation in human fibroblasts.

The interaction of bradykinin (BK) with its specific receptors on intact cultured human fibroblasts results in production of prostaglandins, including prostacyclin (PGI2), and accumulation of cyclic AMP. Incubation of cells with 1 microM BK for 5 min at 37 degrees C led to a marked reduction (75-90%...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Roscher, A A, Manganiello, V C, Jelsema, C L, Moss, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1984
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC370507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6146639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI111452
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