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Altered Calcium Influx Pathways in Cancer-Associated Fibroblasts

Cancer-associated fibroblasts (CAFs) represent an important component of the tumour microenvironment and are implicated in disease progression. Two outstanding questions in cancer biology are how CAFs arise and how they might be targeted therapeutically. The calcium signal also has an important role...

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Principais autores: Francisco Sadras, Teneale A. Stewart, Mélanie Robitaille, Amelia A. Peters, Priyakshi Kalita-de Croft, Patsy S. Soon, Jodi M. Saunus, Sunil R. Lakhani, Sarah J. Roberts-Thomson, Gregory R. Monteith
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-06-01
Serier:Biomedicines
Fag:
breast cancer
cancer-associated fibroblasts
calcium
calcium signalling
voltage-gated calcium channels
store-operated calcium entry
Online adgang:https://www.mdpi.com/2227-9059/9/6/680
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