Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine.

The antihistamine [3H]mepyramine binds to H1 histamine receptors in mammalian brain membranes. Potencies of H1 antihistamines at the binding sites correlate with their pharmacological antihistamine effects in the guinea pig ileum. Specific [3H]mepyramine binding is saturable with a dissociation cons...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Tran, V T, Chang, R S, Snyder, S H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1978
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393167/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/282646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.12.6290
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