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IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts

Activation of the innate immune system plays a key role in exacerbations of chronic lung disease, yet the potential role of lung fibroblasts in innate immunity and the identity of epithelial danger signals (alarmins) that may contribute to this process are unclear. The objective of the study was to...

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Bibliografski detalji
Glavni autori: Suwara, M I, Green, N J, Borthwick, L A, Mann, J, Mayer-Barber, K D, Barron, L, Corris, P A, Farrow, S N, Wynn, T A, Fisher, A J, Mann, D A
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931585/
https://ncbi.nlm.nih.gov/pubmed/24172847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.87
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