A Sequence Variant in the Phospholipase C Epsilon C2 Domain Is Associated With Esophageal Carcinoma and Esophagitis

A single-nucleotide polymorphism (rs2274223: A5780G:His1927Arg) in the phospholipase C epsilon gene (PLCε) was recently identified as a susceptibility locus for esophageal cancer in Chinese subjects. To determine the underlying mechanisms of PLCε and this SNP in esophageal carcinogenesis, we analyze...

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Detalhes bibliográficos
Main Authors: Wang, Li-Dong, Bi, Xiuli, Song, Xin, Pohl, Nicole M., Cheng, Yulan, Zhou, Yixing, Shears, Stephen, Ansong, Emmanuel, Xing, Mengtao, Wang, Shaomeng, Xu, Xiao-Chun, Huang, Peng, Xu, Liyan, Wang, Liang, Fan, Zongmin, Zhao, Xueke, Dong, Huali, Meltzer, Stephen J., Ding, Ivan, Yang, Wancai
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931523/
https://ncbi.nlm.nih.gov/pubmed/23390063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22016
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