Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma

Esophageal cancer (EC) ranks sixth in cancer death. To explore its genetic origins, we performed exomic sequencing on 11 adenocarcinomas (EAC) and 12 squamous cell carcinomas (ESCCs) from the United States. Interestingly, inactivating mutations of NOTCH1 were identified in 21% of ESCCs but not in EA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Agrawal, Nishant, Jiao, Yuchen, Bettegowda, Chetan, Hutfless, Susan M., Wang, Yuxuan, David, Stefan, Cheng, Yulan, Twaddell, William S., Latt, Nyan L., Shin, Eun J., Wang, Li-Dong, Wang, Liang, Yang, Wancai, Velculescu, Victor E., Vogelstein, Bert, Papadopoulos, Nickolas, Kinzler, Kenneth W., Meltzer, Stephen J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473124/
https://ncbi.nlm.nih.gov/pubmed/22877736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0189
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