Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma

Esophageal cancer (EC) ranks sixth in cancer death. To explore its genetic origins, we performed exomic sequencing on 11 adenocarcinomas (EAC) and 12 squamous cell carcinomas (ESCCs) from the United States. Interestingly, inactivating mutations of NOTCH1 were identified in 21% of ESCCs but not in EA...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Agrawal, Nishant, Jiao, Yuchen, Bettegowda, Chetan, Hutfless, Susan M., Wang, Yuxuan, David, Stefan, Cheng, Yulan, Twaddell, William S., Latt, Nyan L., Shin, Eun J., Wang, Li-Dong, Wang, Liang, Yang, Wancai, Velculescu, Victor E., Vogelstein, Bert, Papadopoulos, Nickolas, Kinzler, Kenneth W., Meltzer, Stephen J.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473124/
https://ncbi.nlm.nih.gov/pubmed/22877736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0189
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires