Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma

Esophageal cancer (EC) ranks sixth in cancer death. To explore its genetic origins, we performed exomic sequencing on 11 adenocarcinomas (EAC) and 12 squamous cell carcinomas (ESCCs) from the United States. Interestingly, inactivating mutations of NOTCH1 were identified in 21% of ESCCs but not in EA...

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Detalhes bibliográficos
Main Authors: Agrawal, Nishant, Jiao, Yuchen, Bettegowda, Chetan, Hutfless, Susan M., Wang, Yuxuan, David, Stefan, Cheng, Yulan, Twaddell, William S., Latt, Nyan L., Shin, Eun J., Wang, Li-Dong, Wang, Liang, Yang, Wancai, Velculescu, Victor E., Vogelstein, Bert, Papadopoulos, Nickolas, Kinzler, Kenneth W., Meltzer, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473124/
https://ncbi.nlm.nih.gov/pubmed/22877736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0189
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