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Molecular Control of δ-Opioid Receptor Signaling

Opioids represent widely prescribed and abused medications, although their signal transduction mechanisms are not well understood. Here we present the 1.8Å high-resolution crystal structure of the human δ-opioid receptor (δ-OR), revealing the presence and fundamental role of a sodium ion mediating a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Fenalti, Gustavo, Giguere, Patrick M., Katritch, Vsevolod, Huang, Xi-Ping, Thompson, Aaron A., Cherezov, Vadim, Roth, Bryan L., Stevens, Raymond C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931418/
https://ncbi.nlm.nih.gov/pubmed/24413399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12944
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