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Molecular Control of δ-Opioid Receptor Signaling
Opioids represent widely prescribed and abused medications, although their signal transduction mechanisms are not well understood. Here we present the 1.8Å high-resolution crystal structure of the human δ-opioid receptor (δ-OR), revealing the presence and fundamental role of a sodium ion mediating a...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931418/ https://ncbi.nlm.nih.gov/pubmed/24413399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12944 |
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