Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity

Using an integrative approach in which genetic variation, gene expression, and clinical phenotypes are assessed in relevant tissues may help functionally characterize the contribution of genetics to disease susceptibility. We sought to identify genetic variation influencing skeletal muscle gene expr...

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Autori principali: Keildson, Sarah, Fadista, Joao, Ladenvall, Claes, Hedman, Åsa K., Elgzyri, Targ, Small, Kerrin S., Grundberg, Elin, Nica, Alexandra C., Glass, Daniel, Richards, J. Brent, Barrett, Amy, Nisbet, James, Zheng, Hou-Feng, Rönn, Tina, Ström, Kristoffer, Eriksson, Karl-Fredrik, Prokopenko, Inga, Spector, Timothy D., Dermitzakis, Emmanouil T., Deloukas, Panos, McCarthy, Mark I., Rung, Johan, Groop, Leif, Franks, Paul W., Lindgren, Cecilia M., Hansson, Ola
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2014
Soggetti:
Genetics/Genomes/Proteomics/Metabolomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931395/
https://ncbi.nlm.nih.gov/pubmed/24306210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1301
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