A Role for Intestinal Alkaline Phosphatase in the Maintenance of Local Gut Immunity

BACKGROUND AND AIMS: Intestinal alkaline phosphatase (IAP) is a gut mucosal defense factor known to dephosphorylate lipopolysaccharide (LPS); however, the role of IAP in the gut response to luminal bacteria remains poorly defined. We investigated immune responses of wild-type (WT) and IAP-knockout (...

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Autors principals: Chen, Kathryn T., Malo, Madhu S., Beasley-Topliffe, Laura Kline, Poelstra, Klaas, Millan, Jose Luis, Mostafa, Golam, Alam, Sayeda N., Ramasamy, Sundaram, Warren, H. Shaw, Hohmann, Elizabeth L., Hodin, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931260/
https://ncbi.nlm.nih.gov/pubmed/20844955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-010-1396-x
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