Persistence of LPS-Induced Lung Inflammation in Surfactant Protein-C–Deficient Mice

Pulmonary surfactant protein-C (SP-C) gene–targeted mice (Sftpc(−/−)) develop progressive lung inflammation and remodeling. We hypothesized that SP-C deficiency reduces the ability to suppress repetitive inflammatory injury. Sftpc(+/+) and Sftpc(−/−) mice given three doses of bacterial LPS developed...

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Auteurs principaux: Glasser, Stephan W., Maxfield, Melissa D., Ruetschilling, Teah L., Akinbi, Henry T., Baatz, John E., Kitzmiller, Joseph A., Page, Kristen, Xu, Yan, Bao, Erik L., Korfhagen, Thomas R.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2013
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931093/
https://ncbi.nlm.nih.gov/pubmed/23795648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0374OC
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