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Macrophage Dysfunction and Susceptibility to Pulmonary Pseudomonas aeruginosa Infection in Surfactant Protein C-Deficient Mice()
To determine the role of surfactant protein C (SP-C) in host defense, SP-C-deficient (Sftpc(−/−)) mice were infected with the pulmonary pathogen Pseudomonas aeruginosa by intratracheal injection. Survival of young, postnatal day 14 Sftpc(−/−)ice was decreased in comparison to Sftpc(+/+) mice. The se...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344318/ https://ncbi.nlm.nih.gov/pubmed/18566429 |
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