Macrophage Dysfunction and Susceptibility to Pulmonary Pseudomonas aeruginosa Infection in Surfactant Protein C-Deficient Mice()

To determine the role of surfactant protein C (SP-C) in host defense, SP-C-deficient (Sftpc(−/−)) mice were infected with the pulmonary pathogen Pseudomonas aeruginosa by intratracheal injection. Survival of young, postnatal day 14 Sftpc(−/−)ice was decreased in comparison to Sftpc(+/+) mice. The se...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Glasser, Stephan W., Senft, Albert P., Whitsett, Jeffrey A., Maxfield, Melissa D., Ross, Gary F., Richardson, Theresa R., Prows, Daniel R., Xu, Yan, Korfhagen, Thomas R.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344318/
https://ncbi.nlm.nih.gov/pubmed/18566429
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