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Identification of an l-Phenylalanine Binding Site Enhancing the Cooperative Responses of the Calcium-sensing Receptor to Calcium
Functional positive cooperative activation of the extracellular calcium ([Ca(2+)](o))-sensing receptor (CaSR), a member of the family C G protein-coupled receptors, by [Ca(2+)](o) or amino acids elicits intracellular Ca(2+) ([Ca(2+)](i)) oscillations. Here, we report the central role of predicted Ca...
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Hauptverfasser: | , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Biochemistry and Molecular Biology
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931085/ https://ncbi.nlm.nih.gov/pubmed/24394414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537357 |
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