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Multiple Ca(2+) Binding Sites in the Extracellular Domain of Ca(2+)-Sensing Receptor Corresponding to Cooperative Ca(2+) Response
A small change in the extracellular Ca(2+) concentration ([Ca(2+)](o)) integrates cell signaling responses in multiple cellular and tissue networks and functions via activation of Ca(2+)-sensing receptors (CaSR). Mainly through binding of Ca(2+) to the large extracellular domain (ECD) of the dimeric...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2627791/ https://ncbi.nlm.nih.gov/pubmed/19102677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8014604 |
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