Identification of an l-Phenylalanine Binding Site Enhancing the Cooperative Responses of the Calcium-sensing Receptor to Calcium

Functional positive cooperative activation of the extracellular calcium ([Ca(2+)](o))-sensing receptor (CaSR), a member of the family C G protein-coupled receptors, by [Ca(2+)](o) or amino acids elicits intracellular Ca(2+) ([Ca(2+)](i)) oscillations. Here, we report the central role of predicted Ca...

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Main Authors: Zhang, Chen, Huang, Yun, Jiang, Yusheng, Mulpuri, Nagaraju, Wei, Ling, Hamelberg, Donald, Brown, Edward M., Yang, Jenny J.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2014
主題:
Signal Transduction
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931085/
https://ncbi.nlm.nih.gov/pubmed/24394414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537357
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